Immunopathogenetic and Pharmacological Aspects of Interstitial Lung Diseases

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Immunopathogenetic and pharmacological aspects of interstitial lung diseases.

Interstitial lung diseases (ILDs) are inflammatory diseases characterized by slow and progressive destruction of alveolar-capillary functional units, often leading to respiratory failure and death. A first stage of alveolitis and a following stage of fibrosis provoke an anatomical distortion of the peripheral airways and the interstitium, and for their smoldering evolution and non-specificity o...

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Interstitial lung diseases (ILDs) are a heterogenous group of diseases with a complex pathogenesis. Inflammation was noticed first to be a component of ILDs, but anti-inflammatory therapy proved effective only in a subgroup of disease entities with predominant inflammatory features such as nonspecific interstitial pneumonia (NSIP), desquamative interstitial pneumonia (DIP) or cryptogenic organi...

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Occupational Interstitial Lung Diseases.

OBJECTIVE Evidence-based diagnostic and treatment guidelines for occupationally related interstitial lung diseases (ILDs) have been developed and are summarized herein. METHODS Comprehensive literature reviews were conducted with article abstraction, critiquing, objective grading, and evidence table compilation. A multidisciplinary expert panel drafted evidence- and consensus-based guidance. ...

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There are few areas of pulmonary disease in which the terminology has been more confusing than interstitial lung disease (ILD ). The interstitium of the lung is made up of the formed elements of the lung bronchi, arteries and veins, interlobular septa, bronchioles, alveolar walls, and the connective tissue which holds everything together This is contrasted with the alveolar spaces, which are es...

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ژورنال

عنوان ژورنال: International Journal of Immunopathology and Pharmacology

سال: 2010

ISSN: 2058-7384,2058-7384

DOI: 10.1177/039463201002300401